Skin Diseases in Systemic Illnesses

Which of the following is a classic skin manifestation of systemic lupus erythematosus (SLE)? *

Erythema nodosum

Malar rash

Livedo reticularis

Bullous pemphigoid

Gottron’s papules are pathognomonic for which systemic disease? *

Scleroderma

Dermatomyositis

Psoriatic arthritis

Rheumatoid arthritis

Acanthosis nigricans is commonly associated with: *

Addison’s disease

Diabetes mellitus

Vitiligo

Hypothyroidism

What is the most common skin manifestation of diabetes? *

Necrobiosis lipoidica

Erythema multiforme

Pyoderma gangrenosum

Sweet’s syndrome

Livedo reticularis is often associated with which systemic condition? *

Rheumatoid arthritis

Antiphospholipid syndrome

Crohn’s disease

Multiple sclerosis

Which autoimmune disease commonly presents with digital ulcers and Raynaud’s phenomenon? *

Systemic sclerosis

Sjögren’s syndrome

Dermatomyositis

Mixed connective tissue disease

Which inflammatory bowel disease is associated with pyoderma gangrenosum? *

Crohn’s disease

Celiac disease

Irritable bowel syndrome

Gastroesophageal reflux disease (GERD)

Which systemic disease is associated with "salt and pepper" skin pigmentation? *

Systemic sclerosis

Addison’s disease

Psoriasis

Hyperthyroidism

Which cutaneous finding is associated with reactive arthritis? *

Keratoderma blennorrhagicum

Butterfly rash

Bullous pemphigoid

Pemphigus vulgaris

Which malignancy is strongly associated with acanthosis nigricans? *

Gastric adenocarcinoma

Hepatocellular carcinoma

Renal cell carcinoma

Pancreatic cancer

Hybrid - Skin Symposium 2025

Skin Diseases in Systemic Illnesses